China Wuhan Desheng Biochemical Technology Co., Ltd Company News

In the fields of biochemical testing and medical diagnosis, the chromogenic substrate TOOS (N-ethyl-N - (2-hydroxy-3-sulfopropyl) -3-methylaniline sodium salt) is an important reagent widely used in the detection of blood glucose, uric acid, liver function, and other items. However, TOOS may undergo oxidative degradation under certain conditions, which can affect the accuracy and reliability of its detection results. This article will explore in detail the causes, influencing factors, and preventive measures of TOOS oxidation deterioration. Reasons for oxidation and deterioration of TOOS The oxidative deterioration of TOOS is mainly due to its reaction with oxygen or other oxidizing substances in the air, resulting in a change in chemical structure and the loss of its original activity and color development ability. Specifically, the oxidative degradation of TOOS may be influenced by the following factors: 1. Oxygen in the air: TOOS has reducibility, and prolonged exposure to air can cause it to react with oxygen, leading to oxidation and deterioration. This oxidation reaction will alter the chemical properties of TOOS, causing it to lose its original color rendering ability. 2. Temperature: High temperatures accelerate the rate of chemical reactions, including oxidation reactions. If TOOS is exposed to high temperatures during storage or use, it will accelerate its oxidation and deterioration process. Therefore, storage temperature is an important factor affecting the stability of TOOS. 3. Humidity: Excessive humidity may cause TOOS to absorb moisture from the air, form hydrates, or undergo other chemical reactions, thereby affecting its stability and activity. 4. Light exposure: Prolonged exposure to light may cause photochemical reactions in TOOS, producing free radicals or other active substances, which can lead to oxidative degradation. 5. Impurity contamination: If TOOS is contaminated with oxidative impurities during preparation or storage, these impurities may accelerate its oxidation and deterioration process. Therefore, the purity of raw materials and the cleanliness during preparation and storage are crucial for the stability of TOOS. Factors affecting TOOS oxidation deterioration In addition to the direct causes mentioned above, the oxidative deterioration of TOOS may also be influenced by the following factors: 1. Material of storage container: Storage containers of different materials may have different effects on the stability of TOOS. For example, certain plastic containers may release harmful substances that react with TOOS, leading to oxidative deterioration. 2. Storage time: Long term storage may cause TOOS to gradually lose activity, and even under good storage conditions, oxidation and deterioration may occur due to time factors. 3. Usage: When using TOOS, improper operation, such as not preparing the solution according to the specified ratio in the manual, not fully mixing, etc., may also affect its stability and color development effect. Measures to prevent TOOS oxidation and deterioration To extend the shelf life of TOOS and maintain its activity, the following preventive measures can be taken: 1. Storage conditions: Store TOOS in a low temperature, dry, and dark environment, such as a refrigerator (recommended temperature is 2-8 ° C). Avoid prolonged exposure to high temperatures, high humidity, or light conditions. 2. Storage container: Choose a storage container with stable material and no harmful substance release, such as glass bottles or stainless steel containers. Avoid using plastic containers that may release harmful substances. 3. Ready to use: When using TOOS, the principle of ready to use should be followed to avoid color changes caused by prolonged storage. The prepared solution should be used up as soon as possible to avoid prolonged storage. 4. Raw material purity: When preparing TOOS, the purity of the raw materials should be ensured and the use of raw materials containing oxidative impurities should be avoided. At the same time, cleanliness should be maintained during preparation and storage to avoid contamination. 5. Operating standards: When using TOOS, it should be strictly prepared and used according to the proportions and operating steps specified in the instructions. Ensure that the solution is thoroughly mixed to avoid errors caused by improper operation. Conclusion The chromogenic substrate TOOS has wide applications in biochemical detection and medical diagnosis, but its oxidative degradation problem cannot be ignored. By understanding the causes, influencing factors, and preventive measures of TOOS oxidation deterioration, we can better protect its stability and activity, thereby improving the accuracy and reliability of detection. In practical applications, we should strictly adhere to storage and usage standards to ensure that the quality and performance of TOOS are fully utilized. Meanwhile, with the continuous advancement of science and technology and the emergence of new chromogenic substrates, we should actively explore and apply more stable and sensitive chromogenic substrates to meet the needs of clinical testing and scientific research. Desheng specializes in producing more than ten the new Trinder's reagents, including TOOS. After more than ten years of research and development, it can ensure that TOOS appears as a powder with a purity of up to 99.5%, strong water solubility, and stable performance to ensure the accuracy of experimental results. Desheng has a place in the market for in vitro diagnostic kit raw materials with high-quality products, and is deeply trusted and supported by customers at home and abroad. If you have any relevant intentions, please click on the official website for consultation!

In the fields of biomedical and clinical diagnosis, the chromogenic substrate TOPS reagent (N-ethyl-N - (3-sulfopropyl) -3-methylaniline sodium salt) plays an indispensable role as a key component in biochemical detection kits. Its unique chemical structure and properties enable TOPS to exhibit excellent colorimetric performance and stability in various biochemical tests, providing strong support for medical diagnosis. However, the purity of TOPS has a significant impact on the accuracy and reliability of experimental results, which cannot be ignored. 1, TOPS purity and experimental accuracy Purity is one of the important indicators for evaluating the quality of chemical substances, and for the colorimetric substrate TOPS, its purity directly affects the accuracy of biochemical detection experiments. TOPS with low purity may contain impurities, which may cause non-specific reactions with the test substance or interfere with the normal color reaction of the target substance. Specifically, if TOPS contains impurities with similar color development characteristics to the target substance, these impurities may competitively react with other components in the color development system, resulting in lower or higher measurement values of the target substance. This situation not only leads to deviations in experimental results, but may also mislead doctors' diagnostic decisions, thereby having adverse effects on patients' treatment. 2, TOPS purity and experimental stability In addition to affecting experimental accuracy, the purity of TOPS is also directly related to the stability of experimental results. TOPS with low purity may be more prone to decomposition or reaction with other substances during storage and use, resulting in decreased performance. This performance decline not only affects the stability of the current batch of experimental results, but may also cause fluctuations in experimental results between different batches or time points. This fluctuation not only increases the uncertainty of the experiment, but may also affect subsequent data analysis and conclusion judgment. Therefore, high-purity TOPS is a key factor in ensuring the consistency and reliability of experimental results. 3, TOPS purity and experimental repeatability The repeatability of experimental results is one of the important indicators for evaluating the reliability of experimental methods. Low purity TOPS may lead to reduced reproducibility of experimental results, which means that experiments may need to be repeated to verify the accuracy of the results. This not only wastes time and human resources, but also increases experimental costs. In addition, if the experimental results are inaccurate, subsequent research based on these results may also lose its significance, further increasing the risk and cost of scientific research investment. On the contrary, high-purity TOPS can reduce the variability of experimental results, improve the repeatability and reliability of experiments, thereby reducing the number and cost of repeated experiments. This is very important for both researchers and clinical diagnostic doctors. 4, TOPS Purity and Cost Control Although high-purity TOPS may mean higher production costs, in the long run, choosing high-purity TOPS is actually a more cost-effective choice. Because high-purity TOPS exhibits good stability during storage and use, with longer shelf life and better stability. This means that the waste of reagents and the cost of repeated experiments caused by performance degradation can be reduced. In addition, high-purity TOPS can improve the accuracy and reliability of experimental results, reducing the risk of misdiagnosis and mistreatment caused by inaccurate experimental results. All of these can provide patients with more accurate and reliable diagnostic services, improving the quality and efficiency of medical care. 5, Conclusion In summary, the purity of the chromogenic substrate TOPS has a significant impact on the accuracy and reliability of experimental results. High purity TOPS can not only improve the accuracy and stability of experimental results, but also reduce experimental costs and risks. Therefore, when selecting and using TOPS, priority should be given to its purity to ensure the accuracy and reliability of experimental results. Meanwhile, by optimizing raw material selection, synthesis process, purification steps, and quality control strategies, the purity of TOPS can be further improved to meet the needs of scientific research and clinical diagnosis. Desheng specializes in producing more than ten the new Trinder's reagents, including TOPS. After more than ten years of research and development, it can ensure that TOPS appears as a powder with a purity of up to 99.5%, strong water solubility, and stable performance to ensure the accuracy of experimental results. Desheng has a place in the market for in vitro diagnostic kit raw materials with high-quality products, and is deeply trusted and supported by customers at home and abroad. If you have any relevant intentions, please click on the official website for consultation!

In the rapidly developing field of in vitro diagnostics (IVD), every technological innovation and breakthrough means that the industry is moving towards more efficient and accurate diagnosis. In 2025, as the global IVD industry elite focuses on China, a grand event that gathers wisdom and innovation - the China International Clinical Laboratory Equipment and Supplies Exhibition (CACLP) - is about to kick off. At this annual feast, Hubei Xindesheng Material Technology Co., Ltd. (hereinafter referred to as "Xindesheng") sincerely invites every colleague dedicated to the field of in vitro diagnostics to join hands, explore the future, and promote the prosperous development of the IVD industry. Innovation leads, jointly building the future of IVD As a member of the IVD industry, Xindesheng has always adhered to innovation driven development and production of in vitro diagnostic reagents since its establishment. Our product line covers multiple fields such as blood collection tube additives, biological buffering agents, chemiluminescence reagents, chromogenic substrates, enzyme preparations, etc., aiming to provide comprehensive reagents for clinical diagnosis. At the upcoming CACLP exhibition, Xindesheng will bring a series of latest research and development achievements, including high-sensitivity detection reagents. These innovative products not only improve the accuracy and speed of diagnosis, but also provide strong support for clinical decision-making. Technical exchange, exploring the forefront of the industry together CACLP is not only a platform for showcasing new products, but also a bridge for deep communication and cooperation within the industry. Xindesheng is well aware that open sharing of technology is the key to promoting industry progress. Therefore, we have set up a special exchange area to have in-depth discussions with our peers attending the exhibition on the latest trends, technological challenges, regulatory policies, and other hot topics in the field of IVD. In addition, the technical team of New Desheng will also answer participants' questions on site, share our valuable experience in product research and development, production quality control, etc., and promote the barrier free flow of knowledge and technology. Collaboration Bridge, Seeking Global Development Together In the context of globalization, international cooperation in the IVD industry is becoming increasingly important. With years of experience in international market development, Xindesheng has established a sales network covering multiple countries and regions such as Asia, Europe, and the Americas. During the CACLP exhibition, we look forward to face-to-face communication with partners from all over the world to explore cooperation opportunities. Whether it is raw material supply, technological upgrading, market expansion, or joint research and development, Xindesheng is willing to serve as a bridge to promote the deep integration of the global IVD industry chain, jointly respond to market challenges, and share development opportunities. Take responsibility and build a healthy future together While pursuing technological innovation and commercial success, Xindesheng never forgets its corporate social responsibility. We are well aware that high-quality in vitro diagnostic reagents have immeasurable value in improving public health and safeguarding people's health. Therefore, Xindesheng has always been committed to improving product quality, following the highest international standards, and ensuring that every reagent can accurately and safely serve clinical use. At the CACLP exhibition, we will showcase our efforts and achievements in quality control, environmentally friendly production, and call on more peers to join this noble mission and contribute to building a community with a shared future for human health. Conclusion: Hand in hand, create brilliance together CACLP in 2025 is not only an exhibition, but also a collision of ideas and a fusion of wisdom. Xindesheng sincerely invites every colleague in the IVD industry, whether you are industry veterans, technical experts, or entrepreneurs of emerging enterprises, to visit our booth (booth number: 4-A 0003), so that we can inspire inspiration through face-to-face communication and create brilliance through cooperation. Let's join hands and write our own wonderful chapter on the global IVD stage!

Carbomers are effective at increasing viscosity in aqueous systems at relatively low levels, with most carbomers capable of producing viscosities of 10,000–60,000 cP when used at only 0.5% w/w. Therefore, carbomers are commonly used as aqueous thickeners in various products. However, the real use of carbomer lies in its ability to impart high yield values ​​to formulations. Yield value is the resistance of a fluid to initial flow when stress is applied, and at rest, a tightly packed carbomer microgel network behaves as an elastic solid that resists deformation. The network does not begin to flow until a critical level of shear stress (i.e. yield stress) is applied, at which point the microgels can slide past each other, resulting in fluid flow. When heterogeneous phases, such as emulsion droplets, are dispersed in a carbomer-thickened formulation, the microgel network captures and stabilizes them against fluids at rest, ie, below the yield stress. However, when a stress in excess of the yield stress is applied, the fluid flows smoothly, enabling product dispensing and application. For this reason, carbomer is used to formulate countless products. Carbomer is easily dispersed in water and mixtures of polar organic solvents and water, such as 70% w/w ethanol-water. When initially prepared, aqueous dispersions of hydrated carbomer particles are acidic and typically exhibit a pH of 2.5-3.5, depending on the polymer concentration. These dispersions do not have significant viscosity and may be cloudy prior to neutralization with alkaline pH adjusters such as sodium hydroxide or triethanolamine. After neutralization of the carboxylate groups, the carbomer becomes ionized and expands to hundreds of its original volume due to electrostatic repulsion between the negatively charged carboxylate groups and osmotic expansion due to trapped counterions times to obtain a microgel dispersion. Hubei Xindesheng Material Technology Co., Ltd. is a professional manufacturer of carbomer. It has a professional carbomer R&D and production team with 17 years of experience and rich product knowledge. There are 940 and 980 models of Carbomer currently produced. The product has stable performance and good use effect. Free samples can be provided for a small test, if you need to buy, please feel free to inquire and buy!

Bicine buffer is dihydroxyethyl glycine, CAS No. 150-25-4. It is a very versatile biological buffer with same excellent buffering performance as Tris.It has gradually replaced traditional phosphate buffered saline in some demanding biochemical tests. Bicine is a slightly acidic amino acid derivative with pH buffer range 7.6-9.0.It’s soluble in water and common organic solvents such as DMF, DMSO, DMAc, etc. Sodium hydroxide is usually added into powdered Bicine to adjust the pH value to meet the PH environment requirements for experiments or testing. If the experimental environment needs to eliminate the interference of sodium ions, potassium hydroxide can be used instead of sodium hydroxide, and then the pH meter can be used to adjust the mixing ratio of Bicine solution and lye solution. The buffering principle of Bicine is similar to the other biological buffers.Bicine is amphoteric, when acid and alkali are added to the reaction system or the pH of the reaction environment changes as the reaction proceeds, it can play a buffering role and maintain the reaction system. It is very important to biochemical detection which involved enzymes or proteins and nucleic acids. The stability and functionality of most organic biomolecules are very sensitive to pH. The molecular structure of Bicine buffer is similar to that of glycine. The hydrogen on the nitrogen atom of the amino group is replaced by two hydroxyethyl groups, which reduces the hydrolysis ability, improves its stability, and maintain the properties of amino acids and aminoethanols that can form gold complex as a single anion.The buffer system configured with Bicine and sodium hydroxide will not participate in the chemical reaction of the reaction system, nor will it interfere with the experimental reaction, and is resistant to chemical action and enzymatic hydrolysis. Desheng is a manufacturer specializing in the production and development of raw materials for biochemical testing and in vitro diagnosis. It has rich experience in blood pretreatment, blood pretreatment and biochemical kits. At present, the mature product series include blood collection tube additives, chromogenic substrate, chemiluminescence reagents and more than ten biological buffers including Bicine.

In serum testing, coagulants can be selected to rapidly coagulate blood, while in whole blood or plasma testing, different anticoagulants are selected to prevent coagulation of collected venous blood.What are the commonly used anticoagulants? Hubei Xindesheng Materials Co., Ltd. has compiled some points of anticoagulants for us. The anticoagulation principle of citrate is forming a chelate with calcium ions in the blood to prevent blood coagulation,such as sodium citrate.The color of citrate blood collection tubes are blue or black head.The ratio of anticoagulant to blood in the blue head tube is 1:9 and in the black head tube is 1:4.The blue-headed tube is often used for determinations of blood coagulation,and the black-headed tube is used for erythrocyte sedimentation rate. The anticoagulation principle of EDTA is forming chelate with calcium ions in the blood to prevent blood coagulation such as EDTA-K2.The head of EDTA tubes are in purple.It normally used in blood routine examination, blood cell morphology examination. The anticoagulation principle is oxalate reacts with calcium ions to form calcium oxalate precipitation, thereby preventing blood coagulation. Such as sodium oxalate, ammonium oxalate, etc.The head of oxalate tubes are in gray.It is often mixed with sodium fluoride which can inhibit glucose glycolysis for blood glucose determination. Heparin is a physiological anticoagulant which widely present in human tissues such as liver and lung. It takes effect by enhancing the activity of antithrombin III (AT-III), inactivating serine protease and preventing the formation of thrombin, such as lithium heparin, sodium heparin, etc.The head of heparin tubes are in green.It normally used in various biochemical tests. In addition, Wuhan Desheng Biochemical Technology Co., Ltd. is a professional blood test reagents in research and development, production and sales. We are an established company specializing in the production of anticoagulant raw materials used in blood collection tubes, including sodium heparin, lithium heparin, dipotassium EDTA, tripotassium EDTA, disodium EDTA, potassium oxalate, trisodium citrate, sodium fluoride, etc.Welcome your consultation.

Chromatography is often used for the separation and purification of proteins in laboratory.In this process, the PH variations is related to the separation capability of the system. If the PH of solvent is near to pKa, for example, small changes in PH can strongly affect retention, and consequently the separation results.A buffer should be added to the system in order to control the mobile phase PH, Since the retention of ionizable compounds is especially sensitive to the PH variable. According to relevant literature in chromatography,we found that although the Tris base and MES are often the best choices for this technique, other buffers have also been used in cation exchange chromatography, anion exchange chromatography, high-performance liquid chromatography (HPLC) and other similar techniques.Below are the 10 best buffers for your reference. 1) BIS-TRIS buffer Suitable PH range: 5.8 - 7.2 PKA (25°C): 6.46 Molecular weight: 209.2g/mol Used as a buffer during anion exchange chromatography (Concerns: several components in a chromatographic system may be competing for metal binding with this buffer) 2) BES buffer Suitable PH range: 6.4 - 7.8 PKA (25°C): 7.09 Molecular weight: 213.2g/mol Used as a binding buffer and eluent in cation exchange chromatography / as a buffer in gel filtration chromatography 3) Bicine buffer Suitable PH range: 7.6 - 9.0 PKA (25°C): 8.26 Molecular weight: 163.2 g/mol Used as a mobile phase buffer and eluent in cation exchange chromatography 4) CAPS buffer Suitable PH range: 9.7 - 11.1 PKA (25°C): 10.40 Molecular weight: 221.32g/mol Used as a binding buffer and eluent in cation exchange chromatography Read more about Hopax CAPS 5) HEPES buffer Suitable PH range: 6.8 - 8.2 PKA (25°C): 7.48 Molecular weight: 238.3g/mol Used as a binding buffer and eluent in cation exchange chromatography in a two-stage reverse dialysis method for in vitro release testing 6) MES buffer Suitable PH range: 5.5 - 6.7 PKA (25°C): 6.10 Molecular weight: 195.2g/mol Used as a buffer in capillary electrochromatography,gel-filtration chromatography,phosphocellulose column chromatography,hydrophobic interaction chromatography,and cation exchange chromatography 7) MOPS buffer Suitable PH range: 6.5 - 7.9 PKA (25°C): 7.14 Molecular weight: 209.3g/mol Used as a running buffer for protein purification in chromatography 8) PIPES buffer Suitable PH range: 6.1 - 7.5 PKA (25°C): 6.76 Molecular weight: 302.37g/mol Used as a buffer in cation exchange chromatography,it should be used in lower concentrations due to its large ionic strength and dependence of concentration on pKa.And a buffer in phosphocellulose chromatography to purify microtubule proteins 9) TAPS buffer Suitable PH range: 7.7 - 9.1 PKA (25°C): 8.40 Molecular weight: 243.28g/mol Used as a buffer in planar chromatography to separate dyes,and in ion exchange chromatography for enzyme purification14 10) Tris buffer Suitable PH range: 7.5 - 9.0 PKA (25°C): 8.06 Molecular weight: 121.14g/mol Used as a buffer and eluent in anion exchange chromatography,and in capillary electrochromatography due to its low ionic mobility Hubei New Desheng Material Technology Co.,Ltd is specialized in producing biological buffer over years.We’ve developed a series of biological buffers including TRIS, HEPES, TAPS, MOPS, CAPS, BICINE, EPPS, PIPES and so on. It’s not only have a large market share in the domestic market, but also have been sold to dozens of countries around the world. We’ve established long-term and stable cooperation with many large-scale biomedical technology enterprises. For more information, pls contact visit our website.

Tripotassium ethylenediaminetetraacetate, abbreviation is EDTA-K3.As an amino polycarboxylate, it has a strong ability to bind metal ions.And it’s often used as a compounding agent for hard water softeners, removal of scale in boilers,rare element separation agent, antidote for heavy metal mercury, etc. The EDTA K3 produced by our company is mainly used as an anticoagulant in vitro in blood collection tubes to deal with blood samples in the process of clinical blood collection and testing. Dissolving the EDTA-K3 powder with a certain amount of distilled water,a solution of the required concentration prepared.The inject it into the blood collection tube to form an EDTA-K3 anticoagulant. EDTA-K3 is liquid in glass blood collection tubes and mist in plastic one. After the EDTA-K3 in the blood collection tube contacts the blood sample, it conjugates and blocks the calcium ions coagulation effect in the blood,and stops the blood coagulation from the external source. EDTA-K3 does not destroy the components of blood cells.It has no effect on the number and size of white blood cells, and hardly affects the shape of red blood cells. It is often used in routine blood tests such as separating and testing of platelets. Combined with our sodium fluoride and separating gel, the anticoagulation effect of EDTA-K3 will be better. The anticoagulation of EDTA-K3 is reversible over a certain period of time. So to ensure the accuracy of the test results, please complete the test within 24 hours. Compared with sodium citrate anticoagulants and lithium heparin anticoagulants, EDTA-K3 is more effective in inhibiting platelet aggregation.When EDTA-K3 anticoagulation was used for blood analysis, unexplained low platelet counts were found. Therefore, it is not suitable for the examination of platelet kinetic energy. As an anticoagulant, it is not suitable for coagulation experiments.Due to its excellent ability to conjugate metals, it naturally cannot be used in systems containing calcium, potassium, sodium, iron and other metal ions. In addition, EDTA-K3 cannot be used for the determination of alkaline phosphatase and leucine peptidase. Hubei Desheng is committed to producing high-quality, high-character EDTA-K3 powder We strictly control the pH value, temperature, impurities and drying time of the production solution. Our factory sells directly with competitive price. Welcome new and frequent customers to inquiry.

The principle of Trinder's reaction is also known as enzymatic method.Under the action of peroxidase, hydrogen peroxide, 4-aminotipyrine (4-AAP), a red quinoneimine compound generates for the determination of light absorption,which is one of in vitro diagnostic reagent method.It is mostly used in biochemical diagnostic reagents to detect liver function, kidney function, blood sugar, blood lipids, etc. Trinder's reaction is to mix the corresponding the new Trinder's reagent, 4-AAP, oxidase and peroxidase to the item to be tested in an appropriate ratio, then add biological buffer and the test substance to cause a color reaction.The value of the item to be measured is calculated by measuring the absorbance of the red quinoneimine compound in the color reaction product. The enzyme in the reaction has specificity and can catalyze the reaction of a specific substance in a targeted manner, ensuring the accuracy of the detection. The biological buffer ensures that the reaction is carried out in the appropriate PH value of the corresponding enzyme. Traditional Trinder's reagents are phenols (phenol, 4-chlorophenol or sodium 2,4-dichloro-6-phenolsulfonate, etc.) and anilines (N,N-dialkylaniline, N,N-Dialkyl-m-toluidine,etc). Phenols have a small absorption wavelength range, and the substances in the test may interfere with the test results. Aniline chromogen substrates need to be carried out under acidic conditions, which limits the use of enzymes, so they cannot be widely used in practical detection. Compared with the traditional Trinder's reagent, the new Trinder's reagent has higher water solubility, a wider range of ultraviolet absorption waves of the color reaction product, a wider range of acid-base reaction requirements, and a more sensitive reaction, so it is more practical in biochemical reactions. There are 9 kinds of new Trinder’s reagents independently developed by Desheng, TOOS, TOPS, ADOS, ADPS, ALPS, DAOS, HDAOS, MADB, MAOS, all of which are white crystalline powders with a purity of over 99%. If the content of the item to be tested is little in serum, ALPS, TOOS, TOPS should be used because they are more sensitive to color; if accurate detection is required, MADB, MAOS can be selected, which have higher absorption wavelengths and not easily interfered by other substances; TOOS, ADOS, DAOS color reaction products are stable and not easy to fade; MAOS is suitable for the determination of wavelengths between 550nm-600nm. Desheng is not only a high-quality manufacturer of the above-mentioned the new Trinder’s reagents, our company can also provide raw materials for biological buffers, which provides convenience for your one-stop shopping with more competitive prices. Welcome to inquiry.

Luminol, also known as 3-Aminophthalohydrazide, a kind of white powder at room temperature. It is a strong acid after being configured into a solution, which has a certain stimulating effect on eyes, skin and respiratory tract. When the luminescent ammonia base solution is treated with an oxidizing agent, the released energy exists in the form of photons, and the wavelength acts as a visible blue light. Therefore, when luminol is treated with nitrogen dioxide, PAN, hydrogen peroxide, ozone and other atmospheric oxidants, it will emit blue light. Based on this principle, luminol is the most common chemiluminescent substance. The following will introduce you the applications of Luminol: 1.Luminol can be used for Arabidopsis thaliana immune-related reactions in Luminol peroxidase-based analysis. 2. As a chemiluminescent substrate Luminol Can be used to detect opsonization and phagocytosis function. 3. As a biodetector. It can be used to detect polymorphonuclear leukocyte (PMNL) response in patients with myeloperoxidase deficiency (MPO). 4. Metal cation analysis, using simple and inexpensive instruments with luminol, can detect metal ions at the part-per-billion level. 5. For glucocorticoid detection and analysis. 6.In biology, luminol is used to detect the presence of copper, iron and cyanide in cells. Usually, a mixed aqueous solution of hydrogen peroxide and a hydroxide base is used as stimulated agent. 7.Testing blood in forensic medicine. Iron in hemoglobin in the Blood catalyze the decomposition of hydrogen peroxide, turning it into water and monooxygen. Monooxygen reoxidizes luminol to make it glow. When detecting blood stains, luminol reacts with heme emitting blue-green fluorescence. This detection method is extremely sensitive. The investigator sprays a solution of luminol and an activator in the area to be investigated, and iron in the blood immediately catalyzes the luminol reaction, which emit a blue light. After the bloodstain is treated with luminol, the DNA of the genetic material it contains has not been destroyed, and can be extracted for identification.When using luminol to detect blood stains, the standard forensic solution containing alkaline luminol and sodium perborate may react with industrial substances which contains copper and living substances such as pesticides, glues, parsnips, radishes to emit light . That can interfere with the detection of hemoglobin in the blood. In this case, the light-emitting substances can be distinguished by the wavelength of the light. Hubei New Desheng Material Technology Co., Ltd. is a professional manufacturer of chemiluminescence reagent Luminol, which can be stored in the dark at 2-8°C for up to 12 months. After 17 years of R&D and production, our products are shipped daily to top research centers and biotech companies in Europe, America and Asia.

Heparin sodium, as a commonly used additive in blood collection tubes, has the main feature of preventing coagulation after blood collection. Because of this, its status has gradually become "noble" in the field of medical testing. In addition, it can also be used as a drug for the prevention and treatment of thrombotic diseases, such as: cerebrovascular thrombosis, which can effectively avoid the formation and expansion of thrombus. From its anticoagulation function, it can be known that it is almost closely related to blood, so how does it affect blood and thus play a role? As an in vitro anticoagulant and anticoagulant drug, it mainly has a great interference effect on the blood coagulation process, and its effects are mainly in the following aspects: 1. First, control the composition of thrombin at the source, so that prothrombin is blocked, and the source of blood coagulation is blocked, so it can no longer promote the formation of thrombin. 2. When it is in a higher concentration, heparin will inhibit the effect of other coagulation factors of the same type, and promote the change of fibrinogen to fibrin. 3. When the above links are affected, the platelets can be prevented from aggregating and causing damage, and the coagulation function of the blood will fail, so naturally there will be no coagulation phenomenon, which is also the purpose to be achieved in the detection. Since the types of heparin sodium on the market are divided into crude heparin sodium and high-quality heparin sodium, as an additive in test tubes, it is necessary to ensure pure appearance, refined and purified high-quality heparin sodium, and the key index data can only be selected if it meets the standards. And in order to achieve a more ideal anticoagulant effect during use, the conventional dosage is 1mL of blood corresponding to 20IU of heparin sodium, remember not to use too much or add it in violation of regulations. Choosing a high-quality heparin sodium manufacturer is an issue that must be considered. As a Chinese blood collection tube additive manufacturer, Desheng has invested a lot of time and money in heparin research. Complete in accordance with all production procedures and production indicators to ensure that there is no problem with the quality of heparin. The heparin products produced today have been fully sold, can provide customers with first-class services, and have experience in cooperation with many overseas companies. If you have relevant needs, welcome to click the website to consult details!

Lithium heparin green tube is a blood collection tube for plasma collection in blood testing. Due to this kind of medical device has the effect of anti-coagulation, the plasma can be separated from the blood after blood collection.Except for the collection of plasma required for biochemical tests,it’s also used for subsequent cell culture experiments of blood cells such as lymphocytes after blood collection. However, this method cannot be used for the test items of white blood cell count and classification, which may lead to inaccurate test results. Lithium heparin blood collection tubes can mainly check liver diseases, such as viral hepatitis or liver cancer,liver abscesses and fatty livers. Lithium heparin is not a test items, but a anticoagulants. With the effect of antithrombin,lithium heparin are added to the blood collection tube with the green cap,which can prolong the coagulation time of the specimen. It is suitable for red blood cell fragility test, blood gas analysis, hematocrit test, erythrocyte sedimentation rate and general energy biochemical determination, but not suitable for blood coagulation test. There is a 3ml tubes with lithium heparin green tubes which is often used for lead detection in children.Lithium heparin green tube is a heparin anticoagulant tube.Heparin sodium was used in the past may influence the result of electrolyte measurement. After technical improvement,lithium heparin is generally used. It can be applied for most biochemical tests, such as serum potassium. Heparin anticoagulants are generally used for emergency laboratory tests, because they need to be centrifuged immediately after blood collection.The yellow or red test tubes need blood coagulation before centrifuging the serum, which will delay the emergency examination.In addition, the lithium heparin green tubes can also be used for trace element determination and blood flow experiments. The plasma separation tubes with light green cap, which is adding lithium heparin anticoagulant to the inert serum separation gel tube.This kind of tubes can separate plasma rapidly , and it is the best choice for electrolyte testing routine plasma biochemical testing and emergency plasma biochemical testing such as ICU. Plasma samples can be loaded directly on the machine and keep stable for 48 hours under refrigeration. Heparin anticoagulation tubes are applied to check four kinds of blood coagulation. It is a common inspection item in the laboratory department,generally to maintain the natural form of red blood cells.If this situation is detected, some traditional Chinese medicine can be used for conservative treatment. Hubei New Desheng Material Technology Co.,ltd is specialists for all kins of blood collection tube additives, which made from good quality of raw materials, welcome to inquity.