China Wuhan Desheng Biochemical Technology Co., Ltd Company News

On April 8, 2025, the Shanghai National Convention and Exhibition Center welcomed the grand opening of the 91st China International Medical Equipment Fair (CMEF). As a benchmark for the medical industry both domestically and internationally, this exhibition, with the theme of "Innovative Technology, Leading the Future with Intelligence", has attracted nearly 5000 companies from more than 30 countries and regions to participate. The exhibition area covers 320000 square meters and is expected to attract over 200000 professional visitors. In this industry feast focusing on cutting-edge technologies such as AI medicine, gene sequencing, surgical robots, etc., Hubei Xindesheng Material Technology Co., Ltd. (booth number: 8.2ZA31) has become one of the focuses of the in vitro diagnostics (IVD) exhibition area with its advantages in the full range of IVD reagent raw materials. 1, Exhibition Overview: Empowered by Technology, Leading the Future with Intelligence This year's CMEF focuses on "AI+Robotics" and has built a full industry chain ecosystem covering 22 themed exhibition areas such as medical imaging, in vitro diagnostics, and medical electronics. Cutting edge technologies such as AI medicine, 3D bioprinting, and digital therapy, along with tens of thousands of innovative products, have been showcased, showcasing new achievements in medical technology. In addition, nearly a hundred forums and academic conferences were held simultaneously, focusing on hot topics such as policies and regulations, market development, and medical engineering transformation. Nearly a thousand industry experts gathered to explore the future trends of the medical industry. 2, New Desheng showcases its full range of products at CMEF In the in vitro diagnostic exhibition area, Hubei Xindesheng has set up booth 8.2ZA31 to comprehensively showcase its technical strength and product matrix in the field of IVD reagent raw materials. As a domestic IVD reagent raw material advantage R&D and production manufacturer, Xindesheng showcased its full range of IVD core raw materials, including: (1) Biological buffering agents: HEPES, MOPS, Tris, CAPS, Tris HCL, BICINE, TAPS, MOPSO, PIPES, etc; (2) Luminescent reagents: 7 types including luminol, isoluminol, and acridine ester; (3) Enzyme preparations: adenosine deaminase, pyruvate kinase, cholesterol oxidase, glycerol kinase, uricase-2, etc; (4) Chromogenic substrates: TOOS, MAOS, DAOS, TOPS, ADOS, ADPS, ALPS, etc Covering mainstream technology platforms such as chemiluminescence and enzyme-linked immunosorbent assay. During the exhibition, it attracted customers from multiple regions abroad to stop and exchange ideas. With the promotion of the policy of volume based centralized procurement, the profit margin of biochemical diagnostic reagents has narrowed, while immune diagnosis (especially chemiluminescence) and molecular diagnosis have become growth engines. As one of the few domestic enterprises with full supply chain capabilities, Xindesheng has demonstrated strong competitiveness in the import substitution process of luminescent reagents and chromogenic substrates. 3, Deeply cultivating raw materials for 20 years, empowering downstream manufacturers to diagnose the future As the crowd of CMEF gradually dispersed, what Hubei Xindesheng left behind at booth 8.2ZA31 was not only a highlight moment for product display, but also a firm step towards domestic substitution of IVD raw materials. From accurate regulation of biological buffering agents, to breakthroughs in sensitivity of luminescent reagents, and to the domestic and international market layout of enzyme preparations, Xindesheng has proven with 20 years of technological accumulation that raw material quality is the core driving force for the upgrading of diagnostic technology and an important guarantee for enterprise development. The New Desheng booth will continue to be open until April 11th. On August 23rd, ZA31, we sincerely invite you to explore the new future of IVD raw materials together!

In the fields of biochemistry and molecular biology, protein transmembrane technology, especially Western Blot (protein immunoblotting) experiments, is an important means of studying protein expression, localization, and function. The selection of biological buffering agents is crucial in ensuring the success of the experiment during this process. CAPS (3- (cyclohexylamine) -1-propanesulfonic acid) has demonstrated unique advantages as an efficient biological buffering agent in protein transmembrane processes. This article will delve into the application of CAPS buffer in protein translocation, including its chemical properties, mechanism of action, operational points, and specific applications in practical experiments. Chemical properties and buffering capacity of CAPS CAPS, The full name is 3- (cyclohexylamine) -1-propanesulfonic acid, which is a white crystalline powder with zwitterionic properties. This wide buffering range enables CAPS to provide a stable pH environment under various experimental conditions. As a biological buffer, CAPS not only has high chemical stability, but also is easily soluble in water, making it easy to prepare and use. In addition, CAPS has low toxicity and good compatibility with biomolecules such as proteins and nucleic acids, making it an ideal choice for biochemical experiments. The mechanism of CAPS in protein translocation In Western Blot experiments, proteins are first separated by SDS-PAGE electrophoresis and then transferred onto PVDF or nitrocellulose (NC) membranes. This process is called protein translocation. CAPS, as one of the main components of membrane transfer buffer, functions through the following aspects: 1. Maintain pH stability: The buffering capacity of CAPS can resist possible acid-base changes during membrane transfer, ensuring that proteins on the membrane maintain their natural conformation and charge state, which is beneficial for subsequent antibody incubation and detection. 2. Promote protein transfer: The components in the CAPS buffer (such as methanol) can affect the solubility and charged state of protein, thus promoting the transfer of protein from gel to membrane. Especially for high molecular weight proteins, CAPS buffer often exhibits better transfer efficiency. 3. Reduce non-specific binding: Some components in the CAPS buffer can reduce non-specific binding between protein and membrane or gel, thus improving the specificity and clarity of membrane transfer. The specific application of CAPS in protein translocation CAPS buffer is widely used in protein translocation, especially in Western Blot experiments. By using CAPS buffer, researchers can more accurately detect the expression levels of specific proteins in cells or tissues, thereby revealing their mechanisms of action in life activities. In addition, CAPS buffer is also suitable for other types of protein translocation experiments, such as spot hybridization, immunohistochemistry, etc. In these experiments, CAPS buffer can also provide a stable pH environment and efficient protein transfer efficiency, ensuring the accuracy and reliability of the experimental results. Conclusion In summary, the biological buffer CAPS plays a crucial role in the process of protein translocation. Its unique chemical properties and buffering ability make CAPS an indispensable tool in experiments such as Western Blot. By accurately preparing and using CAPS buffer, researchers can optimize the conditions for protein translocation and improve the accuracy and efficiency of experiments. With the continuous development of biochemistry and molecular biology, CAPS buffer is expected to be widely used in more types of protein transmembrane experiments, providing stronger support for life science research. Hubei Xindesheng Material Technology Co., Ltd. specializes in the production of biological buffering agents such as caps. Since its establishment in 2005, the company has a 20-year history of research and development and production. The production process is mature and stable, ensuring product purity of over 99%. The appearance is white powder, with good water solubility and small batch differences. If you have any recent purchasing needs, please click on the official website to learn more about the market or contact me!

In today's rapidly advancing medical technology, every technological leap is a significant improvement in ensuring human health. In the season of spring in 2025, the global medical industry's attention will be focused on Shanghai, and the 91st China International Medical Equipment Fair Spring Exhibition (CMEF) is about to grandly open. At this grand event that gathers the world's top medical technology and innovative achievements, Hubei Xindesheng Material Technology Co., Ltd. (hereinafter referred to as "Xindesheng") will showcase the latest achievements in China's in vitro diagnostic reagent field to the world with its star products, outstanding research and development capabilities, and forward-looking technological vision. Focusing on in vitro diagnostics, deeply cultivating the field of blood vessel additives for blood collection As a leader in the in vitro diagnostic reagent industry, Xindesheng has always been committed to the research and production of key products such as blood collection tube additives, chromogenic substrates, chemiluminescence reagents, and biological buffering agents. For this exhibition, Xindesheng carefully selected some highlight products, aiming to bring more efficient and safer diagnostic solutions to global medical customers. Serum separation gel: displays four different colors of serum separation gel, which not only meets the visual differentiation needs of different laboratories, but also ensures the purity and stability of samples with its excellent separation performance, providing a solid foundation for subsequent testing. Efficient coagulants and anticoagulants: New Desheng provides two types of coagulants suspension and high-efficiency coagulants powder for different detection needs, as well as reagents for different anticoagulant systems such as EDTA dipotassium, tripotassium, heparin sodium, heparin lithium, sodium citrate, potassium oxalate, etc. Whether it is rapid coagulation analysis or the need to maintain liquid samples for a long time, the best match can be found here to ensure the accuracy of test results. High performance silicification agent: Through unique silicification treatment technology, it effectively reduces the interaction between the inner wall of the blood collection tube and the sample, improves the efficiency of sample collection, and ensures the integrity of the sample, creating favorable conditions for high-precision detection. Biological buffer: a solid support for scientific research and clinical practice The selection of buffering agents is crucial in biological research. The series of biological buffering agents brought by Xindesheng, including tris, mops, hepes, caps, ADA, tes, etc., have become the first choice for many scientific research institutions and clinical laboratories due to their excellent pH stability, low toxicity, and wide application compatibility. These buffering agents not only support experimental needs in various research fields from molecular biology to cell culture, but also greatly promote innovation and development of in vitro diagnostic technology. Innovation driven, working together to create the future Xindesheng is well aware that innovation is the core driving force behind the advancement of medical technology. Therefore, the company continues to increase its R&D investment, introduce international advanced equipment and technology, and build a R&D team composed of professional researchers, committed to developing more high-quality products that meet international standards. Through continuous technological innovation and optimization, Xindesheng is gradually building a global sales and service network, providing more convenient and efficient solutions for global customers. CMEF stage, jointly painting a new chapter in healthcare The CMEF Spring Exhibition in 2025 is not only a stage for Xindesheng to showcase its latest technological achievements, but also a valuable opportunity for communication, mutual learning, and common development with industry colleagues. New Desheng looks forward to collaborating with partners, experts, scholars, and representatives of medical institutions from around the world to explore the future trends in the field of in vitro diagnostics, work together to promote the development of global healthcare, and jointly draw a beautiful blueprint for human health. At the upcoming CMEF event, Hubei Xindesheng Material Technology Co., Ltd. cordially invites you to visit our booth and witness the infinite possibilities of medical technology together, creating a brilliant future for a healthy world!

The selection of buffering agents is crucial for the success or failure of biochemical and molecular biology experiments. TAE (Tris acetate EDTA), as a commonly used electrophoresis buffer, plays an important role in DNA electrophoresis, RNA electrophoresis, and related molecular biology experiments due to its high compatibility, stability, and wide range of applications. This article will delve into the high compatibility of TAE buffer, including its composition, mechanism of action, advantages, and specific applications in experiments. Composition and characteristics of TAE buffer TAE buffer is mainly composed of Tris (trimethylaminomethane), acetic acid, and EDTA (ethylenediaminetetraacetic acid). Tris is a zwitterionic compound that provides the required conductivity for solutions and maintains pH stability. Acetic acid, as one of the main components of buffering agents, works together with Tris to form a stable pH environment. EDTA chelates divalent cations (such as Ca ² ⁺, Mg ² ⁺) to inhibit the activity of metal dependent nucleases and protect DNA from nuclease degradation. The characteristics of TAE buffer lie in its excellent buffering capacity and protective effect on DNA. Compared with other electrophoresis buffers such as TBE (Tris borate EDTA), TAE has a slightly weaker buffering capacity, but its protective effect on DNA is more significant. In addition, TAE buffer also has the advantages of low toxicity, high solubility, and easy preparation, making it an ideal choice in molecular biology experiments. The high compatibility mechanism of TAE buffer The high compatibility of TAE buffer is mainly reflected in the following aspects: 1. Wide pH range: TAE buffer buffer is suitable for most DNA and RNA electrophoresis experiments. Meanwhile, TAE buffer can resist the interference of external acids or bases, maintain the pH stability of the reaction system, and ensure the accuracy of experimental results. 2. Protective effect on DNA: EDTA, as an important component of TAE buffer, effectively inhibits the activity of metal dependent nucleases by chelating divalent cations, thereby protecting DNA from degradation by nucleases. This characteristic makes TAE buffer perform well in DNA electrophoresis experiments, ensuring the integrity and clarity of DNA fragments. 3. Low toxicity and high biocompatibility: The components of TAE buffer have low cytotoxicity to human cells and are easily compatible with biomolecules. This makes TAE buffer have broad application prospects in experiments such as cell culture and tissue sectioning. 4. Easy to prepare and store: The preparation process of TAE buffer is simple, convenient, and has good storage stability. This makes TAE buffer easy to manage and use in the laboratory, reducing experimental and time costs. Specific application of TAE buffer in experiments TAE buffer is widely used in biochemical and molecular biology experiments, including but not limited to the following aspects: 1. DNA electrophoresis: TAE buffer is one of the most commonly used buffer solutions in DNA electrophoresis experiments. By using TAE buffer, the size and quantity of DNA fragments can be clearly separated and observed, providing reliable data support for subsequent gene cloning, sequencing and other experiments. 2. RNA electrophoresis: Similar to DNA electrophoresis, TAE buffer is also suitable for RNA electrophoresis experiments. By optimizing electrophoresis conditions, efficient separation and detection of RNA fragments can be achieved, providing a powerful tool for RNA research. 3. Other molecular biology experiments: In addition to electrophoresis experiments, TAE buffer is also suitable for other molecular biology experiments, such as DNA extraction, purification, enzyme digestion reactions, etc. In these experiments, TAE buffer can provide a stable pH environment and appropriate ion strength, ensuring the accuracy and reliability of the experimental results. Conclusion In summary, the biological buffer TAE plays an important role in biochemical and molecular biology experiments due to its high compatibility, stability, and wide range of applications. By delving into the composition, mechanism of action, and advantages of TAE buffer, we can better utilize this tool, optimize experimental conditions, and improve experimental efficiency and accuracy. With advanced production technology and comprehensive sales services, we have won unanimous praise and continuous repeat purchases from numerous customers. If you also have a need to purchase biological buffering agents, please feel free to contact us at any time, or click on our official website for more detailed information. We look forward to establishing a long-term and stable cooperative relationship with you to jointly promote the development of the field of biological buffering agents.

In the fields of biochemistry and molecular biology, the chromogenic substrate ALPS reagent (N-ethyl-N - (3-sulfonylpropyl) aniline sodium salt) has attracted much attention due to its unique chemical structure and efficient reactivity. As a high-performance chromogenic substrate, ALPS's reactivity not only determines its sensitivity and accuracy in biochemical detection, but also lays a solid foundation for its application in multiple fields. This article will delve into the reaction activity principle, applications, and future development prospects of ALPS. The reactive principle of ALPS The chemical structure of ALPS contains specific functional groups that endow it with the ability to efficiently react with enzymes, especially horseradish peroxidase (HRP). When ALPS meets HRP, an oxidation reaction occurs in the presence of hydrogen peroxide. This reaction leads to changes in the structure of ALPS molecules, resulting in significant color changes. This color change is not only intuitive and easy to measure, but also directly proportional to the enzyme content, providing a reliable basis for quantitative analysis of proteins. The reaction mechanism between ALPS and HRP may involve multiple types of chemical reactions, such as redox reactions, acid-base reactions, or coordination reactions. These reactions not only cause changes in color, but may also be accompanied by changes in physical properties such as absorbance, fluorescence intensity, or chemiluminescence. These changes in properties provide rich detection methods for biochemical quantitative analysis. It is worth noting that the reactivity of ALPS is influenced by various factors, including pH value, temperature, and ionic strength. Under suitable conditions, ALPS can bind with target molecules (such as enzymes) to form stable complexes and undergo color changes during this process. Therefore, in practical applications, it is necessary to strictly control these reaction conditions to ensure that the color reaction of ALPS can proceed smoothly. Application of ALPS ALPS has a wide range of applications in the fields of biochemistry and molecular biology, especially in protein detection and analysis. Here are some typical application scenarios: 1. Enzyme linked immunosorbent assay (ELISA): ALPS, as a key component in ELISA technology, its excellent performance enables this technique to detect target proteins more accurately. In ELISA experiments, ALPS is introduced as a chromogenic substrate after binding to the enzyme-linked secondary antibody and primary antibody, and reacts with HRP to generate colored products. The color intensity directly reflects the abundance of the target protein, thus achieving quantitative analysis of the target protein. 2. Western Blot: This technique separates and immobilizes proteins from complex biological samples on membranes by binding specific antibodies to target proteins. Subsequently, the HRP labeled secondary antibody binds to the primary antibody to form an "antigen primary antibody secondary antibody HRP" complex. At this step, ALPS is introduced as a chromogenic substrate and reacts with HRP to generate colored products. The color intensity also directly reflects the abundance of the target protein, providing strong support for qualitative analysis of the protein. 3. Disease diagnosis and prognosis evaluation: The high sensitivity of ALPS makes it an ideal choice for detecting various disease biomarkers. By quantitatively detecting the levels of these proteins, doctors can assist in diagnosing diseases, monitoring disease progression, and evaluating treatment effectiveness. For example, the application of ALPS in the detection of tumor markers and cardiovascular disease-related proteins provides important evidence for early detection and effective treatment of diseases. 4. Protein function research: In proteomics research, the application of ALPS helps scientists identify and validate the function of specific proteins, as well as explore the interaction networks between proteins. This is crucial for understanding basic life processes such as cellular signaling and metabolic pathways. In summary, the chromogenic substrate ALPS has broad application prospects in the fields of biochemistry and molecular biology due to its efficient reactivity. By continuously improving its chemical structure, combining new detection technologies, and optimizing data processing methods, we can further enhance the sensitivity and accuracy of ALPS, providing more reliable support for disease diagnosis and treatment. In the future, ALPS is expected to play an important role in more fields and make greater contributions to the research and development of life sciences. Hubei Xindesheng Material Technology Co., Ltd. specializes in producing the new Trinder's reagents, in addition to A; In addition to PS, there are also TOOS, TOPS, ADOS, ADPS, etc. After more than a decade of dedicated research and development, the technology for producing new Trinder's reagents has become very mature, and the products produced have also been exported abroad. At present, there are over 400 domestic and foreign large, medium, and small new enterprises cooperating with Desheng, and their products and services are widely recognized by users. If you are also interested in the new Trinder's reagent, please click on the official website for consultation. Looking forward to communicating with you!

The new coronavirus is the most terrible word in 2020. There is no doubt that in order to eliminate the fear it brings us, the world is making suggestions for virus detection. Fortunately, with the efforts of scientific researchers, nucleic acid detection is basically Virus carriers have been successfully screened, and methods are needed to have products. In the process of sending nucleic acid samples to be tested, they also need the help of virus transportation media, otherwise the virus nucleic acid will not be detected and will increase. The false negative rate is the so-called missed diagnosis.   There are two commonly used virus transportation media, that is inactivated and activated type. The activated virus transportation media is often infectious due to the virus, which requires very high operating environment and personnel. Once the specimen is contaminated, it will cause unpredictable consequences. In the routine virus nucleic acid detection, if the detection environment does not meet the requirements, it is recommended to use inactivated virus transportation media.   The high concentration of guanidine salt in the inactivated transportation media can quickly inactivate and preserve the respiratory pathogens, making the sample lose its infectivity. Virus DNA/RNA extraction kits can be used for inactivated samples. The M32/M96 nucleic acid extraction instrument can quickly extract nucleic acids. At the same time, it can be used with the respiratory pathogen PCR detection kit to achieve rapid detection. The specific sensitivity is not affected.   Features of inactivated virus transportation media produced by Hubei New Desheng: 1. Easy to use and operate, no liquid preparation is required, and the system contains high-efficiency virus lysate. The virus is inactivated immediately after sampling, effectively preventing the risk of secondary infection and ensuring the safety of transportation and testing personnel; 2. Viral DNA/RNA can be stored and transported at room temperature for 1 week without degradation. After extraction according to most commercial kits, the obtained DNA/RNA has good quality and high yield, and can complete various genetic testing and analysis experiments. Such as PCR, qPCR, etc., while saving transportation costs; 3. Nucleic acid RNase inhibitor is included to maximize the protection of viral nucleic acid from degradation and greatly improve the efficiency of nucleic acid extraction. 4. It is suitable for the collection, storage and transportation of common virus samples such as new coronavirus, influenza virus, hand-foot-mouth virus, etc. It can collect pharyngeal swab nasal test samples or tissue samples of specific parts.   Hubei New Desheng now provides a large number of inactivated and activated virus transportation media for domestic institutions or enterprises to meet the needs of nucleic acid testing.