Wuhan Desheng Biochemical Technology Co., Ltd

The spring breeze brushes over Egret Island, and flowers welcome guests. In the field of in vitro diagnostics (IVD), the China International Conference on Laboratory Medicine and Blood Transfusion Instruments and Reagents (CACLP) has always been a barometer and accelerator for promoting industry development. The 23rd CACLP will be held at Xiamen International Expo Center from March 21 to 23, 2026, with full expectations from the industry. As a leading enterprise deeply involved in the upstream raw material field of IVD, Hubei Xindesheng Material Technology Co., Ltd. will attend the appointment on time, and together with over a thousand global enterprises, we will embark on this industry feast of "moving towards the new and pursuing excellence with quality" on the banks of the blooming Egret Island in spring. New theme leads new trend, Xiamen writes a new chapter again Since its establishment in 1991, CACLP has gone beyond the scope of exhibitions and evolved into a comprehensive and specialized service platform that integrates exhibition display, academic exchange, brand promotion, and supply chain construction. The theme of this grand event is "Moving towards' new 'and achieving long-term goals with' quality '", closely following the new trend of the global in vitro diagnostic industry shifting from high-speed growth to high-quality development. Moving to Xiamen, this year's CACLP has achieved a comprehensive upgrade in scale and experience. It is reported that the exhibition will not only gather exhibitors from more than 20 countries and regions, but also welcome professional visitors from over 50 countries and regions. In addition to the traditional instrument reagents, raw materials, and supply chain exhibition areas, this exhibition will establish a "silent hall" for the first time, creating a more focused and efficient business negotiation environment for exhibitors and professional buyers. At the same time, special exhibition areas and forums focusing on hot topics such as AI smart healthcare, home testing, and enterprise globalization will also bring unprecedented immersive experiences to participants. Deeply cultivating upstream raw materials, New Desheng showcases its strength As a well-known enterprise in the upstream raw material field of IVD in China, Hubei Xindesheng Material Technology Co., Ltd. will showcase its "specialized, refined, and innovative" hard core strength at this grand event. Since its establishment in 2005, Xindesheng has always focused on the research and development, production, and sales of polymer materials and biologics. At the R&D and production base of Ezhou Optics Valley Joint Science and Technology City, the company has successfully created a diversified product matrix covering biological buffering agents, chemiluminescence reagents, chromogenic substrates, etc. through continuous technological accumulation. Its production of Tris, Bicine, Caps and other biological buffering agents, with high purity and excellent stability, has become a solid support behind many biological diagnostic kits; And chemiluminescent reagents such as luminol and acridine ester, as well as new Trinder's reagents such as TOOS and TOPS, play an irreplaceable role in clinical biochemical detection and immunoassay due to their sensitivity. Quality leads to long-term success, Xindesheng sincerely invites you to come and negotiate At the 22nd CACLP, Xin Desheng's brilliant appearance is still fresh in people's memory. In 2026, with a steadfast commitment to quality and a pursuit of innovation, New Desheng will once again embark on a journey of transformation. With the international platform provided by this CACLP, Xindesheng will not only showcase the latest research and development achievements and core products, but also hope to explore the cutting-edge technology trends of IVD upstream raw materials through in-depth exchanges with industry colleagues, scientific research experts, and partners, and seek deeper cooperation opportunities. The company's professional technical and sales team will be stationed at the booth (booth number: 4-A3012) throughout the entire process, answering questions and sharing customized raw material solutions for every visiting guest. The 23rd CACLP is not only a product showcase, but also an industry gathering. From Hangzhou to Xiamen, what has changed is the host location, but what remains unchanged is the original intention of Xindesheng to help the development of the IVD industry. March 21, 2026, Xiamen International Expo Center. Hubei Xindesheng Material Technology Co., Ltd. is ready and cordially invites new and old friends to visit our booth, enjoy tea and discuss the beautiful future of the IVD industry together! Let's make an appointment on Egret Island, don't see each other!  

In the field of biomanufacturing, viscous acid, as an important platform compound, can be widely used in the pharmaceutical, chemical, and materials industries. How to achieve efficient conversion from glucose to viscous acid has always been a focus of researchers' attention. In recent years, the strategy based on co culture of Escherichia coli has provided new ideas for this issue, and MOPS buffer plays an indispensable supporting role in this process. Co cultivation strategy: metabolic mode of division of labor and collaboration Traditional single strain fermentation typically requires the integration of the complete metabolic pathway for the synthesis of viscous acids into a single cell. This method often imposes a heavy metabolic burden on the host bacteria, and the accumulation of intermediate products may also trigger feedback inhibition or cytotoxicity, affecting the final yield. The co cultivation strategy adopts a different approach. Researchers have constructed two functionally complementary engineered strains of Escherichia coli: one responsible for converting glucose into intermediate products, and the other responsible for further converting intermediate products into viscous acids. This modular division of labor mode breaks down complex metabolic tasks into two relatively independent links, reducing the burden on individual strains and minimizing the interference caused by intermediate product accumulation, which helps to improve overall conversion efficiency. Functional positioning of MOBS in co cultivation system In a co culture system, two strains need to grow and metabolize synergistically in the same fermentation environment, which places higher demands on the stability of the culture conditions. MOPS, as a biological buffering agent, mainly plays the following roles in this process: Maintain pH stability. The effective buffering range of MOPS is between pH 6.5 and 7.9, which precisely covers the suitable growth and metabolic range of Escherichia coli. During the fermentation process, bacterial metabolism produces acidic or alkaline substances. If the pH fluctuates too much, it may affect enzyme activity and bacterial growth. MOPS can neutralize these metabolites, stabilize the pH within a narrow range, and provide a relatively stable reaction environment for both strains. Low interference with metal ions. Unlike some buffer systems, MOPS has a lower chelating ability for metal ions. The essential metal ions in the culture medium, such as magnesium ions and calcium ions, can be freely taken up and utilized by bacterial cells without being limited by the presence of buffering agents, which is beneficial for maintaining enzyme activity and normal cellular metabolism. The impact of osmotic pressure is relatively small. MOPS has low permeability to cell membranes and does not cause additional osmotic pressure stress to bacterial cells. In culture media containing inorganic salts, this characteristic helps maintain osmotic pressure balance inside and outside the cell, protecting the structural integrity of the cell. Stable environment and metabolic efficiency In a culture medium composed of MOPS, glucose, and inorganic salts, the two engineered strains can perform their respective functions in a relatively coordinated manner. Module A strain converts glucose into intermediate products in a stable pH environment, while Module B strain utilizes these intermediate products to continue synthesizing viscous acid. The buffering effect of MOPS runs through the entire process, providing a basic guarantee for this division of labor and cooperation. Conclusion With the development of synthetic biology and metabolic engineering, the requirements for the stability of culture systems are constantly increasing. MOPS, as a buffer component in co culture systems, provides basic support for strain co metabolism by maintaining a stable pH environment.   Hubei Xindesheng Material Technology Co., Ltd. focuses on the research and production of biological buffering agents such as MOPS. The products have high purity and good batch stability, which can meet the different needs of scientific research and industrial production. If you need further understanding of MOPS raw materials, please feel free to contact Xindesheng.  

Blood ammonia testing is a fundamental and important clinical indicator in liver function assessment, diagnosis of hepatic encephalopathy, and screening for metabolic diseases. However, the concentration of blood ammonia is extremely low in the blood, and the sample is easily contaminated by exogenous ammonia. The requirements for reagent stability and reaction sensitivity in the detection process are also much higher than those for conventional biochemical tests. How to accurately capture trace changes in blood ammonia in complex clinical samples is the key and difficult point in the development of in vitro diagnostic reagents. Color reaction: the core process of blood ammonia detection The widely used blood ammonia measurement methods in clinical practice are mostly based on the principle of enzyme coupling reaction. The ammonia in the sample reacts with glutamic acid under the catalysis of glutamine synthetase, generating glutamine and consuming ATP; Subsequently, the reaction signal is converted into hydrogen peroxide (H ₂ O ₂) through an auxiliary enzyme system; Finally, under the catalysis of peroxidase (POD), H ₂ O ₂ undergoes oxidative condensation with the chromogenic substrate, generating colored quinone imine compounds whose absorbance is proportional to blood ammonia concentration. The key to this reaction pathway lies in the colorimetric system, which directly determines the strength and stability of the detection signal. If the color reaction is unstable, even if the early enzymatic reaction is accurate, there may still be deviations in the final result. The technical bottleneck of traditional color rendering system The commonly used chromogenic substrates for early blood ammonia detection include 4-aminoantipyrine (4-AAP) and MBTH (3-methyl-2-benzothiazolinone hydrazone). 4-AAP has a lower cost, but its molar absorptivity is not high, which affects the detection sensitivity; At the same time, its water solubility is limited, which restricts the reaction efficiency. Although MBTH has high sensitivity, its chemical stability is poor, especially in the air where it is easily oxidized, leading to the gradual failure of reagents during storage or the operation of fully automatic biochemical analyzers, and the reproducibility of detection results is difficult to guarantee. In the context of pursuing high-throughput and automated testing in clinical laboratories, the onboard stability of colorimetric systems has become an unavoidable technical challenge in reagent development. Introduction of TOOS: From Structural Optimization to Performance Enhancement The application of the novel chromogenic substrate TOOS reagent(N-ethyl-N - (2-hydroxy-3-sulfopropyl) -3-methylaniline) provides a feasible solution to the above problems. The TOOS molecular structure contains sulfopropyl and hydroxyl groups, endowing it with excellent water solubility and steric hindrance effect, which can effectively inhibit the occurrence of non-specific oxidation reactions. In practical applications, TOOS often forms a dual color system with MBTH. Under the catalysis of peroxidase, the two can efficiently couple to form stable quinone imine chromophores, with a maximum absorption wavelength between 550-570 nm and a molar absorptivity of 3.92 × 10 ⁴ L · mol ⁻¹ · cm ⁻¹. The signal intensity is significantly improved. More importantly, with appropriate formulation support, this combined color development system can maintain long-term chemical stability and meet the continuous detection requirements of fully automatic biochemical analyzers. Multiple guarantees of stability In addition to the molecular structure advantage of TOOS itself, the overall stability improvement of the reagent also benefits from the optimization of formula design. In the TOOS+MBTH colorimetric system, an appropriate amount of oxygen scavenger (such as ascorbic acid derivatives) and non-ionic surfactant can be added to protect MBTH molecules and reduce their oxidation risk during storage and use. At the same time, TOOS has stable chemical properties within the physiological pH range and will not cause side reactions with buffer solutions (such as Tris), inorganic salts, or enzyme components, which helps to ensure inter batch consistency of reagents and reduce fluctuations in clinical testing results. This characteristic is particularly important for diagnostic reagents that require long-term storage and cross batch use. Hubei Xindesheng Material Technology Co., Ltd. has long been dedicated to the research and production of high-performance chromogenic substrates such as TOOS, and is committed to providing stable raw material supply and professional technical support for the in vitro diagnostic industry. If you have any recent purchasing needs, please click on the official website to learn more details or contact me directly!  

Spring and clear scenery, gather strength and move forward. In the current rapidly developing clinical diagnosis and biochemical research industry, every industry event is an important platform for technical exchange, resource docking, and collaborative development. As a backbone enterprise in the field of domestic biochemical raw materials, on the occasion of this industry event, Xindesheng officially announced that it will showcase its core products at the 2026 Xiamen CACLP exhibition. We sincerely invite industry colleagues to visit our booth, discuss industry trends, explore new cooperation opportunities, and embark on a new journey of domestic biochemical raw material development. The grand industry event has begun, and we have made an appointment to go to Xiamen together As a highly influential industry exhibition in the field of in vitro diagnostics in China, CACLP brings together core forces such as diagnostic reagent companies, research institutions, distributors, and terminal medical institutions from around the world. It is an important window to showcase cutting-edge technologies, connect with high-quality resources, and gain insights into market trends. Every CACLP exhibition attracts countless industry professionals to gather together, exchange the latest technological achievements, explore industry development pain points, explore potential cooperation opportunities, and promote high-quality development of the in vitro diagnostic industry. In 2026, the CACLP exhibition will be held at the Xiamen International Expo Center, officially opening on March 21 and continuing until March 23, presenting a comprehensive industry feast covering technology, products, and services. To ensure the smooth operation of the exhibition, Xindesheng attaches great importance to it. Not only did it bring the company's core products, but it also prepared a professional technical team to provide professional explanations, product demonstrations, and demand matching services for visiting colleagues throughout the process. We strive to ensure that every friend who visits the booth can gain something and be inspired. Direct access to booth information, no getting lost during appointments For the convenience of colleagues in the industry to quickly find the New Desheng booth and efficiently carry out communication and docking, the relevant information of this CACLP exhibition and the details of the New Desheng booth are now provided in detail as follows. It is recommended that you save them for future use: Core Time of the Exhibition: The exhibition setup will take place on Friday, March 20, 2026 from 8:30 to 18:00, the exhibition will run from March 21, 2026 to March 23, 2026, and the exhibition will be cancelled at 4:00 pm on March 23, 2026; Exhibition address: Xiamen International Expo Center; Hubei Xindesheng booth number: 4-A3012 (Hall 4). Xiamen International Expo Center has convenient transportation and complete supporting facilities. Colleagues can take public transportation or drive to the exhibition site. After arriving at the exhibition site, they can directly go to Hall 4 and quickly find booth 4-A3012 according to the booth number. All exhibitors of Xindesheng will warmly welcome your arrival and have face-to-face communication and discussion with you. Core products debut, unlocking new advantages of domestic substitution Core products: Hubei Xindesheng Materials will showcase the company's core products at booth (4-A0003). As for the blood collection tube additive series, products such as serum separation gel, heparin lithium, heparin sodium, EDTA dipotassium/tripotassium/disodium, coagulant, coagulant powder, etc. will be displayed in sequence. Biological buffering agents will display products such as TRIS, HEPES, MOPS, CAPS, TAPS, etc. Newly invested enzyme preparation products: The company has established an enzyme preparation project team since 2024. At this exhibition, the company will showcase enzyme preparation related products at the CACLP exhibition. Our technical team will explain the characteristics and applications of the products in detail on site and provide professional solutions. On site, the technical team of New Desheng will provide a detailed explanation of the production process, performance advantages, and application scenarios of the product to colleagues. They will also demonstrate the effectiveness of the product and provide professional solutions to the problems encountered in practical applications. Whether you want to understand product parameters, explore innovative applications of products in clinical diagnosis and biochemical research, or seek long-term stable partners, you can find answers at the New Desheng booth. Inviting colleagues to gather and explore the new future of the industry together The CACLP exhibition is not only a platform to showcase the strength of enterprises, but also a bridge for industry colleagues to exchange and cooperate. During this exhibition, Xindesheng not only hopes to showcase domestic in vitro diagnostic products to the industry, but also hopes to use this platform to have in-depth exchanges with industry colleagues, listen to industry needs, explore industry development pain points and future trends, seek more opportunities for cooperation, and work together to promote high-quality development in the fields of in vitro diagnostics and biochemical research. In March, Xiamen, with warm spring and blooming flowers, the grand event begins and we embark on a new journey together. Hubei new desheng is fully prepared and is waiting for industry colleagues to arrive at booth 4-A3012 in Hall 4 of Xiamen International Expo Center. Together, we will explore new directions for industry development and build a new future for the development of domestic biochemical raw materials! Looking forward to meeting you in Xiamen, living up to our encounter, and together we will embark on a beautiful journey!