The Influence Of Different Valences On The Use Of Blood Anticoagulant Heparin Lithium 9045-22-1

Heparin lithium, as a commonly used blood collection tube additive in clinical testing, plays an important role in the medical field due to its unique anticoagulant properties. However, there are significant differences in the use of heparin lithium with different valences, which directly affect the accuracy of blood sample collection, processing, and detection results. This article will explore the impact of different valences on the use of heparin lithium from several key aspects.

Definition and Importance of Potency

Potency refers to the unit of efficacy of heparin lithium in response to blood anticoagulation, and is an important indicator for measuring its anticoagulant effect. Generally speaking, the higher the potency, the more significant the anticoagulant effect of heparin lithium. Common heparin lithium titers include 150IU/mg, 160IU/mg, etc. Heparin lithium with different potency has its own advantages in anticoagulant strength, stability, and applicability.

heparin lithium powder

Anticoagulant effect and blood sample processing

1. Anticoagulation intensity

There are differences in anticoagulant strength among heparin lithium with different valences. High valence lithium heparin can bind more quickly to coagulation factors in the blood, forming stable anticoagulant complexes and effectively prolonging blood clotting time. This is particularly important for blood samples that require long-term storage or transportation, ensuring that the sample maintains a stable anticoagulant state from collection to testing.

2. Sample processing

During the processing of blood samples, heparin lithium with different valences also exhibits different characteristics. High efficiency lithium heparin can more thoroughly inhibit coagulation reactions and reduce the coagulation risk of samples during centrifugation, separation, and other processes. At the same time, its good stability also ensures the consistency of the sample during multiple processing, improving the reliability of the detection results.

Scope of application and testing items

1. Routine biochemical testing

In routine biochemical testing, heparin lithium with different valences has different applicability ranges. Low potency heparin lithium is suitable for testing items that do not require high anti coagulation requirements, such as the determination of some electrolytes, enzymes, and other indicators. High efficiency heparin lithium is more suitable for samples that require long-term storage or transportation, as well as detection projects that require high anti coagulation requirements, such as blood gas analysis, hematocrit experiments, etc.

2. Special testing items

For certain special testing items, such as arterial blood gas analysis, electrolyte detection, calcium ion detection, etc., high valence heparin lithium exhibits superior performance. These projects require extremely high anticoagulant effects on blood samples, and only high-efficiency lithium heparin can ensure the stability and accuracy of the samples during the testing process.

Clinical application and precautions

1. Clinical application

In clinical applications, doctors should choose the appropriate heparin lithium potency based on specific testing items and patient conditions. For example, in biochemical tests of patients after hemodialysis, due to the presence of a certain amount of heparin anticoagulant drugs in the patient's blood, high-efficiency lithium heparin should be selected to ensure sufficient anticoagulation of the sample. In routine biochemical testing, the appropriate potency can be selected according to the specific requirements of the testing items.

2. Precautions

When using heparin lithium with different valences, the following points should also be noted: first, ensure that the blood collection tube is completely dried to avoid bacterial growth of heparin lithium in aqueous solution; Secondly, after the blood collection is completed, the blood collection tube should be gently inverted and mixed as soon as possible to ensure that the blood is fully mixed with heparin lithium; Thirdly, it should be noted that the anticoagulant effect of heparin lithium is not irreversible, and testing should be completed within the specified time to avoid result errors.

Product packaging

In summary, there are significant differences in anticoagulant efficacy, sample processing, applicability, and clinical application among heparin lithium with different valences. Choosing the appropriate potency of heparin lithium is crucial for ensuring the accuracy of blood sample collection, processing, and testing results. Choosing a high-quality heparin lithium manufacturer is equally important. Hubei Xindesheng Material Technology Co., Ltd. has been researching, producing, and selling heparin lithium and other blood collection tube additives for nearly 20 years. Our professional technical team can provide customized services and guarantee after-sales service. If you have any related needs in the near future, please feel free to consult and purchase!