Preparation Of Additives for blood collection vessels 9041-8-1 Heparin Sodium Solution

Heparin sodium, a precious anticoagulant derived from pig intestines, has become an indispensable and important ingredient in the pharmaceutical and cosmetic industries due to its unique physiological activity and wide application value. It not only plays a crucial role in blood vessels and antithrombotic drugs, but also demonstrates its unique skincare effects in cosmetics. Today, we will discuss in detail the preparation, addition, drying, and storage of heparin sodium.

Firstly, let's talk about the preparation and addition of heparin sodium. Heparin sodium usually exists in powder form and needs to be prepared into a solution for use. In the preparation process, we usually use physiological saline as a solvent because it is similar in composition to human blood and does not cause allergic reactions. According to the conventional dose, 1 milliliter of blood corresponds to 20 IU of heparin sodium. Therefore, when preparing the solution, we need to calculate the required amount of heparin sodium based on the amount of blood to be processed. For example, when processing 5 milliliters of blood, we need to add 100 IU of heparin sodium. In vacuum sampling containers, we usually spray heparin sodium solution at a dose of 20-25 microliters on the tube wall to achieve good anticoagulant effect.

heparin sodium powder

Next, let's take a look at whether the heparin sodium solution needs to be dried. Due to the fact that heparin sodium is sprayed on the tube wall in a solution state, it needs to be dried in an oven before use. The purpose of doing so is to reduce the influence of heparin volume on drug concentration in plasma and ensure the stability of anticoagulant effect. Heparin sodium is heat-resistant and usually needs to be dried for a few hours at a temperature of 80 degrees Celsius. However, it should be noted that the dried heparin sodium should be used immediately to avoid performance degradation caused by prolonged storage.

Of course, when preparing and storing heparin sodium solutions, we also need to pay attention to some details. Firstly, heparin sodium solution should be used as soon as possible after preparation to avoid prolonged storage and bacterial growth. Secondly, sodium heparin solution should be stored in a low-temperature environment of 0-4 degrees Celsius to ensure its stability and effectiveness. The longest storage period should not exceed one week to avoid changes in the performance of heparin sodium, which may affect the anticoagulant effect.

As a professional manufacturer of heparin salts, Desheng Biochemical has always been committed to providing customers with high-quality products and services. The heparin sodium and heparin lithium we produce are both high-quality heparin with a titer of up to 150IU/mg, which can meet the needs of various vacuum vascular extraction additives. We have a professional R&D team and after-sales service team, which can provide customers with comprehensive technical support and solutions. If you have any relevant needs, please feel free to contact us at any time, and we will be happy to serve you!