Cas # 35556-70-8 PEP Good Buffer Solutions White Crystal Powder

There is not much information on the biological buffer PEP product on the Internet, and it is basically limited to some basic ones. There is little information on this aspect of a more in-depth understanding of it, even if we want to understand it, there is no way to start. Our Desheng company is a technology-based enterprise integrating R&D, production and sales. We are doing our own efforts in the field of biological buffers. I will now talk about the company’s biological buffer PEP (cas:35556-70-8) Briefly exchange some relevant information with you.

Desheng PEP product packaging

The cytoprotective and antioxidant properties of phosphoenolpyruvate (PEP). Phosphoric acid is a glycolytic metabolite with high-energy phosphate groups. PEP (0.1-10 mM) significantly attenuated the decrease in cell viability induced by hydrogen peroxide (H(2)O(2)) in HeLa cells in a dose-dependent manner. PEP also inhibited the decrease in cells stained with calcein-acetomethoxy and the increase in cells stained with propidium iodide induced by H(2)O(2). 

PEP powder

PEP is a functional carbohydrate metabolite with cytoprotective and antioxidant activities, and may be used as a therapeutic agent for diseases involving oxidative stress. However, it did not show any effect at low doses (0.1, 1 mM). PEP (0.1-10 mM) also reduced cell damage, but did not attenuate the decrease in intracellular ATP content induced by the glycolysis inhibitor 2-deoxy-D-glucose.

PEP can also reduce organ preservation caused by liver preservation for 72 hours, histological changes and oxidative stress parameters (measured by thiobarbituric acid reactive substances and glutathione content) changes in aminotransferase and lactate dehydrogenase Increased leakage. Its effect is comparable to that of the University of Wisconsin solution (a gold standard organ preservative). PEP treatment can alleviate the decrease of ATP content in liver during cold storage. PEP prevents cell damage of cells and increases the content of reactive oxygen species in the cells. In addition, PEP scavenge hydroxyl radicals, but has no effect on superoxide anions, as assessed by electron paramagnetic resonance spin trap technology.

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The product quality and customer service of the material biological buffer PEP produced by Desheng have been recognized by many customers and have been designated as a long-term supplier.