Importance of enzyme preparations used in clinical diagnosis and treatment

Enzymes are highly specialized and complex proteins that contribute to the chemical changes in various parts of the body and exist in every organ and cell in the body. Such as L-homocysteine ​​methyltransferase, S-adenosine homocysteine ​​hydrolase (SAHH), S-adenosylmethionine synthetase, N-acetylneuraminic acid aldolase, fructose amino acid Oxidase, neuraminidase/sialidase, and NRH are all frequently heard words in clinical diagnosis. At the same time enzymes are necessary for your body to function properly.

(1) Enzymes in disease diagnosis
Enzyme diagnosis is a method of diagnosing diseases by measuring the content and changes of certain substances in the body, or by the changes in the activity of the original enzymes in the body. Enzyme diagnostic methods are based on two aspects: changes in the original enzyme activity in the body and changes in certain substances in body fluids. These changes can be detected by enzymes. Phosphatases are hydrolases that catalyze the hydrolysis of phosphate monoesters into inorganic phosphate esters under acidic conditions. Patients with prostate cancer or hyperparathyroidism have elevated serum acid phosphatase activity. Another example: glucose oxidase can be used to detect glucose content in the diagnosis of diabetes; urease can be used to measure urea content to diagnose liver and kidney disease; cholesterol oxidase can be used to measure blood cholesterol content to quickly diagnose hyperlipidemia; Glutaminase can be used to measure the glutamine content in cerebrospinal fluid. DNA polymerase can be used to detect whether the gene is normal or whether there are any oncogenes in the body. It has unique enzymatic characteristics such as high catalytic efficiency and mild action conditions, and enzymatic diagnosis has become a reliable and rapid diagnostic method.

(2) Enzymes in disease prevention and treatment

You may not know that enzymes can be used as drugs to treat many diseases. Common trypsin can be used not only to accelerate wound healing and dissolve blood clots, but also to remove necrotic tissue and inhibit the proliferation of contaminating microorganisms. R-asparaginase can treat cancer by depriving cancer cells of nutrients needed for growth, and proteases (such as multi-enzyme tablets) can be used to treat indigestion and have anti-inflammatory effects. R-asparaginase, soybean meal fibrinolytic enzyme, thrombin, etc. can be used to treat diseases. Many enzymes are used as diagnostic reagents in medical treatments. Because of its remarkable curative effect and insignificant side effects, medicinal enzymes have become more and more widely used in the health field.

Desheng Biochemical has been engaged in the production of enzyme substrate enzyme preparations for many years. Some products are for reference, adenosine deaminase, malate dehydrogenase, cystathionine β lyase (CBL), cystathionine β synthase (CBS), Betaine homocysteine ​​S-methyltransferase, creatinase/sarcosinase, creatinase