Wuhan Desheng Biochemical Technology Co., Ltd

In the field of medical testing, the collection and processing of blood samples are crucial, and EDTA anticoagulant, as a commonly used specimen type, has a profound impact on the accuracy of test results through its correct use and standardized operation. Today, let's delve into the relevant knowledge of EDTA anticoagulant. Reverse blood collection to prevent clots The preparation of whole blood test specimens depends on the adequacy of anticoagulation. After blood collection, the blood collection tube must be reversed 5-8 times as soon as possible. This simple operation step has significant importance as it can effectively prevent the formation of small blood clots. If this operation is ignored, small blood clots may interfere with the subsequent testing process, leading to biased test results and affecting the doctor's judgment of the patient's condition. So, the timely reversal operation after blood collection should not be underestimated. Timely inspection to avoid errors EDTA salt anticoagulation is a non irreversible anticoagulation method, which determines that the EDTA anticoagulation test should be completed within 24 hours after blood collection in the test tube. Once this time limit is exceeded, certain components in the blood may undergo changes, which may lead to errors in the test results. For example, the morphology and function of blood cells may change over time, affecting the detection values of various indicators. Therefore, arranging the inspection time reasonably and ensuring the completion of the testing work within the prescribed time limit is an important prerequisite for ensuring the accuracy of the results. Properly preserve and maintain stability Different blood cell counts have different requirements for storage conditions. White blood cell count can be stored for 48 hours at 4 ℃, while it does not exceed 24 hours at 23 ℃; Platelet count can be stored for 24 hours at 4 ℃. Understanding and following these storage conditions can maximize the stability of blood samples, ensure that the state of blood components during testing is as consistent as possible with that during blood collection, and provide guarantees for accurate testing. Precise quantity control to prevent changes The anticoagulant process requires a sufficient amount of EDTA, but excessive use can cause problems. Excessive EDTA may cause morphological changes in blood cells, which undoubtedly have adverse effects on the test results. Therefore, it is particularly important to accurately control the amount of EDTA dipotassium added. In practical operation, inspectors need to strictly follow the standard operating procedures and accurately measure the amount of EDTA dipotassium to avoid affecting the quality of testing due to improper dosage. Understand the characteristics and apply them reasonably EDTA salt has the effect of inhibiting platelet aggregation, but it should be noted that it cannot completely prevent platelet aggregation. This characteristic requires inspectors to fully consider the possible partial aggregation of platelets when analyzing test results, in order to avoid misjudgment. At the same time, corresponding measures should be taken during the collection and processing of blood samples to reduce the influence of external factors on platelet aggregation. Coordinated use and standardized operation EDTA dipotassium can be used in combination with sodium fluoride and separation gel. When used in combination, there is a clear addition standard, that is, when EDTA dipotassium/sodium fluoride is used, 1.2-2.0mg dipotassium and 2-4mg sodium fluoride should be added per milliliter of blood. Strictly following this standard for operation can ensure that various reagents play their best role, improve the accuracy and reliability of detection. Radiation sterilization to ensure safety After adding relevant substances to the blood collection tube, irradiation sterilization is an essential step. It is recommended to use gamma ray irradiation at a dose of 8-25kGy, which can be determined based on the initial bacterial count. Through irradiation sterilization, microorganisms inside the blood collection tube can be effectively killed, ensuring the sterile state of the blood collection tube, preventing contamination of blood samples during collection and storage, and ensuring the authenticity and safety of test results. The correct use of EDTA anticoagulant involves multiple steps and details, from the processing after blood collection to the control of testing time, from the control of storage conditions to the accuracy of reagent dosage, and then to the standardized operation of sterilization. Each step is closely connected and jointly affects the accuracy of the test results. Only by strictly following these usage precautions can high-quality blood samples be provided for medical testing and reliable basis be provided for disease diagnosis and treatment. Hubei Xindesheng Material Technology Co., Ltd. has been researching and producing blood collection tube additives such as EDTA dipotassium for nearly 20 years. The performance of various products produced not only meets relevant standards, but also meets the customized needs of customers. If you are interested in our products, please click on the official website to learn more details or contact me!  

In the silky texture of cosmetics, the stable efficacy of pharmaceutical products, and the strong adhesion of industrial products, there is a seemingly insignificant substance that plays a crucial role - carbomer. It is like an invisible magician, endowing numerous products with unique performance through clever thickening techniques. Carbopol originally existed in the form of powdered resin, with its molecules tightly curled up like snails curled up in a shell, making its thickening ability difficult to exert. When it is dispersed in water, the molecules will undergo hydration with water, resulting in a certain degree of stretching. However, even if the concentration of the aqueous solution reaches a certain level before neutralization, its thickening effect is still not satisfactory. This is like a dancer with unlimited potential, but constrained by their hands and feet, unable to perform graceful dance moves. The key to unleashing the powerful thickening power of Carbopol is to transform its acidic state into the appropriate salt. This transformation process is like injecting vitality into carbomer molecules. Using inorganic bases such as sodium hydroxide, potassium hydroxide, ammonium hydroxide, or low molecular weight organic amines to neutralize carbomer can ionize its molecules and generate negative charges along the polymer backbone. At this point, the repulsive force between same-sex charges begins to take effect, and the originally curled up molecules quickly straighten out, forming an open structure. This process is fast and efficient, with the thickening effect achieved instantly, and the solution changes from thin to thick and stable. Texture shaper in the field of beauty In the world of cosmetics, Carbopol thickening technology can be regarded as a master in shaping texture. For essence, its texture becomes more mellow and delicate after being thickened by Carbomer. Applied to the skin, it can spread evenly and form a lightweight protective film, giving the skin a silky touch. At the same time, it can also help the effective ingredients in essence to better adhere to the skin surface, improve the absorption efficiency of ingredients, and bring more lasting nourishment to the skin. In the lotion, the thickening effect of Carbomer makes the water oil two phases can be better fused, avoiding the occurrence of stratification, so that the lotion can always maintain a uniform and stable texture, making it more comfortable to use. The Stable Guardian of the Pharmaceutical Industry In the field of medicine, products thickened with carbomer have become the guardians of stability. Some ointment and gel for external use can be applied to the affected part more accurately by virtue of the thickening property of Carbomer. The protective film it forms not only isolates bacteria and pollutants from the outside world, but also has a moisturizing effect, creating a good healing environment for wounds or lesions. At the same time, Carbopol can also release drugs slowly and continuously, improve the efficacy of drugs, reduce the frequency of administration, and alleviate the pain of patients. A reliable helper for industrial applications The industrial sector also relies on the assistance of Carbopol thickening. In paint production, Carbopol thickening can adjust the viscosity of the paint, making it easier to control during the application process. Both brushing and spraying can achieve a uniform effect, improving the quality and appearance of the coating. In terms of adhesives, the thickened carbomer enhances the viscosity and cohesion of the adhesive, improves its bonding strength and durability, enabling it to adapt to more complex working environments and meet the diverse needs of industrial production. With the continuous advancement of technology, Carbopol thickening technology is also constantly innovating. Researchers are exploring more environmentally friendly and efficient neutralizing agents to further enhance the thickening effect of Carbopol and the overall performance of the product. At the same time, the application scope of Carbopol is constantly expanding, and it is expected to play an important role in more emerging fields in the future. The Carbopol produced by Hubei Xindesheng Material Technology Co., Ltd. is mainly used in the cosmetics field. Desheng has rich research and development experience and professional technical personnel. In addition to providing professional usage advice, it can also provide customized services. If you have any purchasing needs in the near future, please feel free to contact me at any time!  

In March 2026, the China International Conference on Laboratory Medicine and Blood Transfusion Instruments and Reagents (CACLP) was grandly held in the beautiful Egret Island of Xiamen. This seaside city has welcomed thousands of companies and tens of thousands of professional visitors from the global IVD industry with an open and inclusive attitude. As the most influential annual event in the field of in vitro diagnostics, this year's CACLP has once again become an important platform for showcasing cutting-edge technologies, exploring industry trends, and facilitating cooperation and exchange. Hubei Xindesheng Material Technology Co., Ltd. made a brilliant appearance with its full range of core products and innovative achievements. During the three-day exhibition, with solid technical strength, excellent product quality, and professional service team, it won widespread attention and high recognition, and successfully concluded, creating a new chapter in the development of the enterprise in Ludao. Ludao showcases its charm, and the full range of New Desheng products showcases its strength The Hubei Xindesheng booth located at Xiamen International Convention and Exhibition Center continues the simple and atmospheric design style, with clear layout and reasonable functional zoning. It not only showcases the professional image of the enterprise, but also creates an open and comfortable communication space for customers. The booth is bustling with people, both new and old, and the enthusiastic atmosphere of consultation and negotiation runs through it. The staff, with full enthusiasm and professional competence, meticulously explained the product features, application scenarios, and technical advantages to each visitor, patiently answered various professional questions, and won high praise and wide recognition from customers. As a company that has been deeply involved in the field of IVD reagent raw materials for many years, Xindesheng showcased its full range of core products such as biological buffering agents, enzyme preparations, chromogenic substrates, and luminescent reagents, fully demonstrating the company's profound accumulation in raw material research and development, large-scale production, and application support. In the field of biological buffering agents, Xindesheng products have a precise pH buffering range, which can stably adapt to the demanding requirements of different detection reactions; In the enzyme preparation series, products such as glucose oxidase and horseradish peroxidase are known for their high activity, excellent stability, and superior batch consistency, playing an irreplaceable role in key enzymatic reaction stages of biochemical and molecular diagnostics. The chromogenic substrate series provides reliable guarantees for the colorimetric detection of various diagnostic reagents due to its high sensitivity, rapid color development, and good water solubility. Innovation driven, continuously leading the development of the industry While showcasing mature products, Xindesheng also actively shared the new progress and achievements made in innovative research and development in recent years. The company firmly believes that innovation is the core engine for enterprise development and the key to winning market competition in the technology intensive field of IVD raw materials. In the past year, Xindesheng has continuously increased its research and development investment, deepened industry university research cooperation, and focused on joint research and development of cutting-edge technologies in the industry. Based on a keen insight into market demand, the company continuously optimizes its product structure and introduces new products. It is worth mentioning that the company has made significant breakthroughs in the field of enzyme preparations, launching new enzyme products with higher catalytic activity and stronger stability, which can effectively meet the diversified needs of downstream customers for high-quality raw materials. Behind these innovative achievements is Xindesheng's firm practice of the development concept of "quality as the foundation, innovation as the wing". Looking ahead to the future, opening a new chapter of development The successful conclusion of the Xiamen CACLP exhibition is another important milestone in the development process of Hubei Xindesheng. Through the exhibition, the company not only demonstrated its technological strength and brand image in all aspects, but also further clarified its future development direction through deep interaction with various parties in the industry. Looking ahead to the future, Xindesheng will continue to adhere to innovation as the guide and quality as the foundation, continuously improving product performance and service level. In terms of product research and development, we will focus on core technology breakthroughs and launch more innovative and competitive raw material products to meet the increasingly diversified needs of the IVD industry. In terms of market expansion, we will actively layout domestic and international markets, deepen strategic cooperation with IVD enterprises, and continuously enhance brand influence and market share. Although the grand event on Ludao has come to an end, the footsteps of Xindesheng have never stopped moving forward. Standing at a new starting point, Hubei Xindesheng will continue to deepen its cultivation in the field of IVD reagent raw materials with a more vigorous attitude, contribute more to the high-quality development of China's in vitro diagnostic industry, and open a more brilliant new chapter.  

In the early stages of life, every expectant parent yearns to know: Is the baby healthy? In the past, obtaining accurate answers often required invasive methods such as amniocentesis, which brought psychological pressure and intangible risks to pregnant women. Nowadays, with just one tube of pregnant woman's venous blood, it is possible to accurately screen for chromosomal diseases in the fetus - this is the revolutionary change brought about by non-invasive prenatal genetic testing. Behind this change, there is an unknown but crucial 'guardian' - free DNA preservation solution. It is pre installed in a special blood collection tube, guarding the trace fetal code in the blood and providing protection for subsequent precise detection. The 'fetal messenger' in maternal blood In 1997, Professor Lu Yuming discovered the presence of free fetal DNA in the peripheral blood of pregnant women, which completely overturned the pattern of prenatal diagnosis. Originally, during pregnancy, placental trophoblast cells undergo normal apoptosis, releasing short DNA fragments into the maternal bloodstream. These fragments are like "miniature messengers" sent from the fetus, carrying all the genetic information of the fetus. However, these messengers are extremely fragile and rare. In early pregnancy, fetal free DNA accounts for only 5% to 10% of the total free DNA in maternal plasma. What's even more concerning is that after the blood is separated from the body, the mother's white blood cells will gradually lyse, releasing a large amount of maternal genomic DNA, which quickly overwhelms these weak fetal signals like a surging tide. If there are no special protective measures, the sample will be "distorted" just a few hours after blood drawing, and cannot truly reflect the chromosomal status of the fetus. Three major functions, precise protection It is in this context that specialized blood collection tubes containing free DNA preservation solutions have emerged. It is not just an ordinary vacuum tube, but a "mobile laboratory" that integrates multiple technological contents. This preservation solution plays three key roles in non-invasive screening: 1. Stabilize blood cells and prevent interference. The preservation solution contains special cell metabolism inhibitors that can quickly penetrate into blood cells, "immobilizing" these nucleated cells from the source and preventing them from rupturing and releasing genomic DNA during transportation. This is like maintaining order in a noisy venue, ensuring that only the original weak signals can be heard, thereby ensuring the purity of the detection background. 2. Protect DNA and resist degradation. There are naturally occurring nucleases in the blood that can cleave free DNA like scissors. The anti nuclease components in the preservation solution can effectively inhibit the activity of these enzymes, like putting a layer of "protective clothing" on precious fetal DNA to protect them from degradation. 3. Transport at room temperature, breaking down barriers. Traditional testing often requires low-temperature cold chain transportation, which is costly and prone to chain breakage. High quality free DNA storage tubes can achieve stable storage at room temperature for up to 3 to 14 days, which means that pregnant women in remote areas can also enjoy testing services that are homogeneous with those in first tier cities. From a tube of blood to a report The role of free DNA preservation solution in non-invasive screening runs through the entire detection process, and every step cannot be separated from its protection: 1. Sample collection and transportation. When nurses use blood collection tubes containing preservation solution to extract blood from pregnant women, protection is immediately activated. The preservation solution quickly mixes into the blood, stabilizing cells and inhibiting nucleases. Subsequently, the sample can be sent to a testing center thousands of miles away at room temperature, without the need for cold chain and without fear of delay. 2. Plasma separation. After receiving the samples, the laboratory separates the plasma through gradient centrifugation. Thanks to the protection of the preservation solution, the original proportion of fetal free DNA is still maintained in the plasma at this time. Without this layer of protection, the separated plasma may have already been contaminated by maternal background DNA, and the test results would be meaningless. 3. Detection and analysis. Extract free DNA from plasma and perform sequencing and analysis. Clinical data shows that samples protected by high-quality preservation tubes have a detection sensitivity and specificity of over 99% for the three most common chromosomal aneuploid diseases - Down syndrome, Edwards syndrome, and Patao syndrome. Hubei Xindesheng Material Technology Co., Ltd. can supply high-quality DNA preservation solution to accurately assist in non-invasive screening production! If you have any purchasing needs in the near future, please feel free to contact me or click on the official website of Desheng to learn more details!